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Hipertensión Arterial/Hypertension

Role of Mediterranean diet in body
mass index in hypertensive and obese patients

Santos R.M., Freitas J., Macedo M.E., Rebelo I.

Centro Estudos Função Autonómica, School Medicine and School Pharmacy,
Oporto University, Portugal.



Hypertension plays an important role in cardiovascular disease. In the presence of hypertriglyceridemia and obesity, just a small increase in the level of blood pressure is necessary for cardiovascular disease to develop.

The aim of the study was to evaluate the effect of a low caloric diet and regular aerobic exercise on systolic and diastolic blood pressure, lipid profile, waist-to-hip circumference (W/H) ratio and weight reduction.

Material and Methods
Forty two overweight/obese subjects (BMI>27 Kg/m2 ), aged 38 ± 12 years were studied. Anthropometrics parameters were measured before prescription of a low caloric diet adjusted to age, gender, physical activity and professional lifestyle. Implementation of aerobic exercise (40 minutes, 3 times for week) was performed as well. The average follow-up was 12 ± 3 months. Blood pressure (BP) and heart rate (HR) parameters were calculated non-invasively during 10 minutes by Finapress® arterial wave. Blood was collected after 12 hours of fasting.

First evaluation vs Last evaluation: Weight (kg) 81.3 ± 13.7 vs 73.5 ± 12.8 ( p<0.05) ; BMI (kg/m2 ) 31.5 ± 4.8 vs 28.7 ± 4.6 ( p<0.0 1); W/H 0.833 ± 0.11 vs 0.781 ± 0.09 ( p<0.05) ; % Body fat 39.6 ± 8.5 vs 36.4 ± 8.1; SBP (mmHg) 142.8 ± 36.0 vs 123.8 ± 27.7 ( p<0.05); DBP (mmHg) 80.9 ± 26.1 vs 66.4 ± 16.7 ( p<0.0 1); HR (bpm) 74.6 ± 9.5 vs 68.7 ± 9.5

Low caloric diet and regular physical exercise induced significant improvement in blood pressure, body mass index, waist-to-hip-circumference, without any change on drug prescription.





December 1st., 2005

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Dr. Diego Esandi
Scientific Committee

Dra. Silvia Nanfara
Scientific Committee
Prof. Dr. Armando Pacher
Technical-Steering Committee



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