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Clopidogrel and Aspirin Versus Ticlopidine
and Aspirin After the Placement of
Coronary Artery Stents

Pedroni, P.; Giachello, F.; Iravedra, J.;
Säger, F.; García Casassa, R.

Hemodinamia Hospital Italiano de La Plata y Clínica 25 de Mayo Mar del Plata,
Cátedra libre de postgrado en Cardiología, Universidad Nacional de
La Plata, Buenos Aires, Argentina

Objective: To compare the safety and efficacy of clopidogrel (c) and aspirin vs. ticlopidine (t) and aspirin after the placement of elective coronary artery stents.

Methods: 97 patients (p) with severe coronary artery disease were included; exclusion criteria were previous anticoagulation, GP IIb IIIa administration, unsuccessful procedure, residual stenosis > ó = 50% and urgent target vassel revascularization. T y C were administred 48 hs. before and 25 days after the procedure, 250 mgr twice and 75 mgr once a day, respectively.

   Clinical evaluation, platelet and haematologic counts were done at 25 th days. All data are show in the following Table 1.

   A p value < ó = 0.05 was considered statistically significant.

Conclusions: Antiplatelet therapy with aspirin and clopidogrel seems to be comparably safe and effective as aspirin and ticlopidine after the placement of coronary artery stents.


Questions, contributions and commentaries to the authors: send an e-mail message (up to 15 lines,
without attachments) to interven-pcvc@fac.org.ar, written either in English, Spanish, or Portuguese.

2nd Virtual Congress of Cardiology

Dr. Florencio Garófalo
Steering Committee
Dr. Raúl Bretal
Scientific Committee
Dr. Armando Pacher
Technical Committee - CETIFAC

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