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Clopidogrel and Aspirin Versus Ticlopidine
and Aspirin After the Placement of
Coronary Artery Stents

Pedroni, P.; Giachello, F.; Iravedra, J.;
Säger, F.; García Casassa, R.

Hemodinamia Hospital Italiano de La Plata y Clínica 25 de Mayo Mar del Plata,
Cátedra libre de postgrado en Cardiología, Universidad Nacional de
La Plata, Buenos Aires, Argentina

Objective: To compare the safety and efficacy of clopidogrel (c) and aspirin vs. ticlopidine (t) and aspirin after the placement of elective coronary artery stents.

Methods: 97 patients (p) with severe coronary artery disease were included; exclusion criteria were previous anticoagulation, GP IIb IIIa administration, unsuccessful procedure, residual stenosis > ó = 50% and urgent target vassel revascularization. T y C were administred 48 hs. before and 25 days after the procedure, 250 mgr twice and 75 mgr once a day, respectively.

   Clinical evaluation, platelet and haematologic counts were done at 25 th days. All data are show in the following Table 1.

   A p value < ó = 0.05 was considered statistically significant.

Conclusions: Antiplatelet therapy with aspirin and clopidogrel seems to be comparably safe and effective as aspirin and ticlopidine after the placement of coronary artery stents.

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2nd Virtual Congress of Cardiology

Dr. Florencio Garófalo
Steering Committee
President
Dr. Raúl Bretal
Scientific Committee
President
Dr. Armando Pacher
Technical Committee - CETIFAC
President
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