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Is Low Ejection Fraction Sufficient to
Define the Prognosis of a Patient or
Should we Characterize the Type of
Dyastolic Dysfunction?

Citelli, José E.; Villarraga, Héctor R.;
Sánchez, Jairo; Badiel, Marisol;
Olaya, Pastor; Rosso, Fernando

Echocardiographic and Hemodinamic Laboratory.
Fundación Valle del Lili, Cali, Colombia

Introduction:Low Ejection Fraction (EF) and restrictive physiology are known factors of poor prognosis. However we do not know if other types of diastolic dysfunction carry also a bad prognosis.

Objective: Define the prognostic value of the non restrictive and restrictive patterns in patients with low EF.

Design: Observational. Bi-directional cohort.

Methods: Patients were selected from the echocardiographic registry between May, 1998 and March 2000 with an EF of <40% with complete diastolic evaluation, an d classified as restrictive (R) and non restrictive (NR). Follow-up was performed by a physician and status regarding death or alive, functional class (FC) and cause of death was done by a phone call. Results: 83 patients, mean age 66 years, EF 30%±8.2, 42 patients were classified in Group R. Mean follow-up of 11±7 months. Mortality rate in group R was 23.8% and 9.7% in group NR. The OR of mortality and FC III-IV group R compared with NR was 5.44 (CI95% 1.92-15.73, p=0.001). There wasn't differences in both groups with respect to FE and demographic characteristics.

Conclusion: Non restrictive diastolic physiology in patients with systolic dysfunction provide a better prognosis than those with restrictive physiology, independent of EF, therefore in large trials their subtypes should be further characterized due to its good prognosis.



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2nd Virtual Congress of Cardiology

Dr. Florencio Garófalo
Steering Committee
Dr. Raúl Bretal
Scientific Committee
Dr. Armando Pacher
Technical Committee - CETIFAC

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