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Oscillations in the Levels of the Free
Hormone T4 in Interventions with
Extracorporeal Circulation

Rodríguez, Justino; Corona, Pedro;
Pérez, Miguel Angel; Pérez, José Luis;
Morillas, Mª Consolación.

Intensive Medical Unit, Clinica "San Roque", Las Palmas G.C.
Intensive Medical Unit, Hospital Militar Central "Gómez Ulla",
Madrid. España.

Objective: To study the variations in the free levels of T4 in interventions with extracorporeal circulation (CEC) during and after of the intervention comparing the results obtained in the cases of bypass aortocoronary (BP) and those of substitution heart valvular (RVC).

Methods: A prospective study, without randomiser, selecting, in the case of RVC to 25 patients, 11 males and 14 females and in the case of BP to 25 males. They are excluded those that present clinical or analytically plasma thyroid hormones levels low or high. They were carried out 5 takings of blood. On 1st, the previous day to the surgery; on 2nd, during the CEC, in the moment of maximum hypothermia; on 3rd, to the arrival to the unit medical intensive; on 4th, the following day of the surgery; on 5th, five days later of surgery. The method statistical employee was the Test t Student among the different extractions accepting as significant the values from lowers than p to 0.05.

Results: The results were in the case of RVC: 1.34 ± 0.43, 1.27 ± 0.30, 1.37 ± 0.42, 1.03 ± 0.32, 1.21 ± 0.47. In the case of BP they were of 1.39 ± 0.30, 1.22 ± 0.35, 1.36 ± 0.50, 1.24 ± 0.39, 1.42 ± 0.45. The statistical analysis demonstrated a significant descent of the values during and after the CEC. However, the values were normalised more in the case of those intervened by BP (p = 0.0152) that in the case of RVC (p = 0.0003), to the first day of the CEC, being normalised totally on 5th day in the two cases.

Conclusions: A significant descent of the free values of T4 is demonstrated during and after an intervention with CEC. However a quicker normalisation exists in the case of a BP that in that of a RVC.



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2nd Virtual Congress of Cardiology

Dr. Florencio Garófalo
Steering Committee
Dr. Raúl Bretal
Scientific Committee
Dr. Armando Pacher
Technical Committee - CETIFAC

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