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Clinical Features and Natural History of
Patients with Hypertrophic Cardiomyopathy
According to Septal Thickness

Lema, L.; Calvo, G.; Balestrini, L.;
Tibaldi, M.; Boccardo, D.; Sala. J.;
Balestrini, C.; Serra, C.

Instituto Modelo de Cardiología-FUCCADIM-Córdoba-Argentina

Objectives: To analyze clinical features of patients (p) with Hypertrophic cardiomyopathy (HCM) and the relationship between septal thickness (ST) and major events (ME) (sudden death) or minor events (me) (heart failure, angor and arrhythmias) during the follow-up period.

Methods: 71 p were included, 48 male (67.6%), mean age 48 (1-83). The p were categorized according with the ST into 3 groups: A) ST between 15 to 19 mm, B) ST between 20 to 29 mm C) ST > a 30mm. The duration of follow-up ranged from 1 to 19 years (mean 5.2)

Results: 36 p had non obstructive HCM and 35 obstructive HCM. 58p showed asymmetric HCM, 7 symmetric HCM and 6 apical HCM. 17 p had family history (FH) of HCM. 41 p were asymptomatic or had mild symptoms, 13 had angor, 9 had dyspnea class III-IV y 9 had syncope. Table 1.

Conclusions: In p with HCM the most common anatomic feature is the asymmetric form, without obstruction. In p with ST > a 30 mm the most common presentation was with obstruction and with predominance of sudden death during follow-up. Those p with ST less than 30 mm had more hospitalizations for angor, heart failure or tachyarrhythmias.



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2nd Virtual Congress of Cardiology

Dr. Florencio Garófalo
Steering Committee
Dr. Raúl Bretal
Scientific Committee
Dr. Armando Pacher
Technical Committee - CETIFAC

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